Chelsea will travel to Old Trafford to face rivals Manchester United who occupy the second spot in the EPL table.
Liverpool in third place will be home to West Ham while Tottenham Hotspur travel to Huddersfield Town.
League leaders, Manchester City and Arsenal will not be in action this weekend as both sides are scheduled to lock horns on March 1.
Saturday February 24 fixtures below…
13:30 Leicester City v Stoke City
16:00 AFC Bournemouth v Newcastle United
16:00 Brighton & Hove Albion v Swansea City
16:00 Burnley v Southampton
16:00 Liverpool v West Ham United
16:00 West Bromwich Albion v Huddersfield Town
18:30 Watford v Everton
Sunday February 25
13:00 Crystal Palace v Tottenham Hotspur
15:05 Manchester United v Chelsea